TUTOPATCH®is a collagenous membrane derived from solvent preserved ?-irradiated bovine pericardium.
The bovine pericardium is subjected to a proprietary, multi-step process – the TUTOPLAST® process - which comprises meticulous cleaning of the tissue and gentle solvent dehydration, monitored by continuous quality controls. As a final step, the product undergoes low-dose ?-irradiation, which renders the product STERILE.
The TUTOPLAST® process provides a thorough inactivation of pathogens, destruction of cells, and removal of cell debris, fat, and non-collagenous protein while preserving the 3-dimensional collagenous structure of the material and the associated biomechanical properties. In addition, the Tutoplast® process leaves no residues which may interfere with the repair process once transplanted into a recipient.
The TUTOPLAST® process is highly active against pathogens and no case disease transmission has been confirmed over the past 35 years. As with all biological products, the transmission of infectious diseases may be ruled out at the level of the ‘state of the art’ only.
Mode of action
Initially, TUTOPATCH® provides a reliable closure of the tissue defect and serves as a scaffold for the cellular repair mechanism, which will replace this scaffold by patient-own tissue. The remodeling process depends on the size of the graft, the regenerative properties of the implant bed, and concomitant conditions, for instance diabetes.
Under undisturbed conditions the remodeling process may take several weeks to several months.
TUTOPATCH is used for replacing or reinforcing connective tissue structures and as a barrier membrane for example in:
Neurosurgery: Duraplasty, dura extension plasty, dura replacement plasty
ENT: Tympanoplasty, duraplasty (fronto- and otobasal), protection of the dura in the case of osseous defects in pneumatised cavities, closure of the cavity entrance in frontal sinus obliterations, closure of nasal septum perforations, coverage of the osseous transition in nasal implants, facial nerve suspension in facial palsy for facial pareses, protection of deep structures after radical neck dissection, suture line protection in the trachea, defect filling after parotidectomy
Oromaxillofacial surgery: Reconstruction of the orbital floor, closure of the maxillary sinus wall, protection of the schneiderian membrane in sinus lift surgery, membrane for guide tissue regeneration and guide bone regeneration
Ophthalmology: Enclosure of filling material, coverage of glaucoma shunts, scleroplasty
Cardiac, thoracic and vascular surgery: Pericardial replacement, replacement of the thoracic wall, suture buttress in pulmonary resection and oesophagus sutures, closure of the retroperitoneum, coverage of vascular prostheses
Abdominal surgery: Reinforcement of the abdominal wall in hernias (caution! abdominal wall replacement), hiatal hernia
Urology: Suture buttress in the case of renal ruptures, patch plasty in renal pole resection, replacement of the tunica albuginea
Gynaecology: Slingplasty in stress incontinence, sacral colpopexy in vaginal prolapse
Orthopaedics: Resectional interpositional arthroplasty
Accident surgery: Reinforcement of primary ligament and tendon sutures
Plastic surgery: Subcutaneous defect filling, subdermal implant for the correction of facial wrinkles
The list of indications does not cover all treatment modalities, in which TUTPATCH® may be used.
- Known hypersensitivity against bovine collagen.
- Any disorder or disease that involves an unacceptable increase in the postoperative risk.
- Full attachment to surfaces, which do not allow immigration of cells or which do not sufficiently provide capillarisation, for instance the application from intraperitoneal to the uninterrupted peritoneum.
The HemiCAP® implants intraoperatively recreate the patients' articular cartilage surface convexities. This unique mapping technology enables the surgeon to place the implant so the implant becomes part of the patient's natural curvatures - both in the medial to lateral aspect as well as the anterior to posterior plane.
RegJoint™ is indicated for arthroplasties in small joints in hand and foot for patients suffering of rheumatoid arthritis or osteoarthritis. The specific target joints are metatarsal I-V, V (MTI I-V) in foot, carpometacarpal (CMC I) and metacarpophalangeal II-V (MCP II-V) joints in hand.
ul. Mławska 13
81-204 Gdynia, Poland
phone: +48 58 776 22 75
fax: +48 58 350 97 57
mobile: +48 506 399 272
Number: PL 92 1020 1853 0000 9502 0124 1017
Bank PKO BP SA, I Oddział w Gdyni
Kod BIC (Swift): BPKOPLPW